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6 Signs That a Liver Detox Is Working

Written by Michael Bayba

Medically Reviewed by Annamarie Coy, BA, ICPR, MATS

6 Signs That a Liver Detox Is Working

There's a limit to how much the liver can detoxify. If your liver is overloaded, diseased, or damaged, it will have difficulty performing its functions.

Reducing the toxins you consume is essential to keep your liver healthy. Here are a few signs of liver detox working properly:

1. More Energy

Toxins impair physical functions. If little to no toxins are circulating in your body, you should feel lighter, refreshed, and energetic.

2. Improved Mental State

A calm physical feeling is tied to a person’s mental state. Detoxification clears the brain of toxins, improving mood and other aspects of mental well-being. This is one reason detox is integral to mental health treatment programs.

The Liver Detoxification Process

The liver detox cycle consists of two steps:

  1. Phase 1: The liver activates a group of enzymes called cytochrome P450. Phase 1 generates a lot of free radicals, which are very reactive molecules that damage cells.

  2. Phase 2: P450 enzymes convert toxins typically stored in fats into water-soluble toxins. This makes the toxins and the free radical byproducts less toxic. The body excretes these byproducts through the bile or urine.

Herbal Supplements

Milk thistle treats liver cirrhosis and liver cancer. It contains an active ingredient called silymarin, a potent antioxidant and anti-inflammatory.

Additional information can be found on the Detox Process at:


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